Which diuretics are sulfa drugs
Gabriel Cooper
Updated on April 13, 2026
What we do know is that there are 2 classes of sulfonamides—those with an aromatic amine (the antimicrobial sulfonamides) and those without (eg, the diuretics acetazolamide, furosemide, hydrochlorothiazide, and indapamide).
What diuretic is safe with sulfa allergy?
Diuretics that do not contain a sulfonamide group (eg, amiloride hydrochloride, eplerenone, ethacrynic acid, spironolactone, and triamterene) are safe for patients with an allergy to sulfa.
Are diuretics sulfa based?
A look at Table 1 shows that most diuretic agents are sulfonamide derivatives. The only diuretics that are not are the potassium-sparing diuretics (triamterene, spironolactone, and amiloride) and ethacrynic acid.
Does hydrochlorothiazide have sulfa in it?
Hydrochlorothiazide (HCTZ) is a sulfonamide-containing drug with commonly reported adverse effects that include electrolyte abnormalities, orthostatic hypotension, hyperglycemia, and photosensitivity.Is Lasix sulfa based?
Although furosemide indeed carries a sulfa moiety, I have not in the past hesitated to prescribe it to patients who are allergic to sulfa antibiotics because I thought cross-reactivity was very unlikely.
Does chlorthalidone have sulfa in it?
The pharmacist reports that the drug interaction system is flagging the chlorthalidone as a problem due to ED’s allergy to SMX since chlorthalidone also contains a sulfa moiety.
Can you take chlorthalidone with sulfa allergy?
Yep, these are safe if you have a sulfa allergy. Thiazide diuretics like chlorthalidone and hydrochlorothiazide (HCTZ) are used to treat high blood pressure and are fine to take even if you’ve been told you have a sulfa allergy to Bactrim.
Can I take lisinopril if I have a sulfa allergy?
You should not use this medicine if you have ever had angioedema, if you are unable to urinate, or if you are allergic to sulfa drugs or to any ACE inhibitor. Do not take hydrochlorothiazide and lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).What drugs should be avoided with sulfa allergy?
- Sulfamethoxazole / trimethoprim (Bactrim, Sulfatrim), a sulfa combination drug that can be taken in liquid or pill form for many types of infections.
- Sulfacetamide (BLEPH-10), drops for eye infections.
- Sulfadiazine silver (Silvadene), a cream to prevent and treat burn infections.
Sulfa Allergy: In patients with sulfa allergy, allergic reaction to Flomax® (tamsulosin hydrochloride) capsules has been rarely reported. If a patient reports a serious or life threatening sulfa allergy, caution is warranted when administering FLOMAX capsules. 4.
Article first time published onIs amlodipine besylate a diuretic?
Amlodipine is a calcium channel blocker that relaxes (widens) blood vessels and improves blood flow. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Can you take amlodipine if you are allergic to sulfa?
You should not take this medicine if you are allergic to sulfa drugs, or if you are unable to urinate.
Can you take losartan if you're allergic to sulfa?
Do not take LOSARTAN-HCTZ if you: are allergic to losartan potassium/hydrochlorothiazide or any of the non-medicinal ingredients in the formulation. are allergic to any sulfonamide-derived drugs (sulfa drugs); most of them have a medicinal ingredient that ends in “-MIDE”.
Can you take acetazolamide If you have a sulfa allergy?
In summary, the risk of reaction to acetazolamide in a patient with sulfonamide allergy is low. However, acetazolamide is listed as possibly cross-reacting with sulfonamide in drug information and the package insert.
Is celebrex a sulfa drug?
Celecoxib, a selective cyclo-oxygenase-2 inhibitor, is a diaryl-substituted pyrazole derivative containing a sulfonamide substituent. Because of this structural component, celecoxib is contraindicated for use in patients who have demonstrated allergic reactions to sulfonamides.
Is Zpack a sulfa drug?
Zithromax and Bactrim belong to different antibiotic drug classes. Zithromax is a macrolide antibiotic and Bactrim is a combination of a sulfonamide antibiotic (a “sulfa” drug) and a folic acid inhibitor.
Why does chlorthalidone make me dizzy?
Chlorthalidone can cause some people to feel lightheaded or dizzy since your blood pressure is being lowered, especially if you’re taking certain other medications or drinking alcohol. Talk to your doctor if you notice any of these symptoms.
Is cephalexin a sulfa drug?
No, Keflex is not a sulfa drug. It is a general antibiotic in the cephalosporin class. It is used for a wide variety of infections. People who have a Penicillin allergy may also be allergic to Keflex.
Is Macrobid a sulfa drug?
Macrodantin is a nitrofuran antibiotic and Bactrim is a combination of a sulfonamide antibiotic (a “sulfa” drug) and a dihydrofolate reductase inhibitor. Side effects of Macrodantin and Bactrim that are similar include nausea, vomiting, and loss of appetite.
What drugs are sulfa drugs?
- Gantrisin (sulfisoxazole)
- Bactrim or Septra (trimethoprim and sulfamethoxazole)
- Sulfadiazine.
- Azulfidine (sulfasalazine)
- Zonegran (zonisamide)
Is Cipro a sulfa drug?
Bactrim (sulfamethoxazole and trimethoprim) is a combination of two antibiotics (a sulfa drug and a folic acid inhibitor) and Cipro (ciprofloxacin) is a quinolone antibiotic. Both drug are used to treat bacterial infections such as urinary tract infections, bronchitis and other lung infections.
Is omeprazole a sulfonamide?
After omeprazole is released from coating, it is converted into active sulfonamide form in the acidic environment (MedicineNet, 2009). This active sulfonamide form is then form covalent bond to cysteine residues to release proton pumps.
Does sulfamethoxazole have sulfa in it?
Sulfa-containing drugs include: sulfonamide antibiotics, including sulfamethoxazole-trimethoprim (Bactrim, Septra) and erythromycin-sulfisoxazole (Eryzole, Pediazole)
Is lisinopril HCTZ a diuretic?
This product contains two medications: lisinopril and hydrochlorothiazide. Lisinopril is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a “water pill” (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water.
Are lisinopril and hydrochlorothiazide the same?
What is hydrochlorothiazide and lisinopril? Hydrochlorothiazide is a thiazide diuretic (water pill). Lisinopril is in an ACE inhibitor (ACE stands for angiotensin converting enzyme). Hydrochlorothiazide and lisinopril is a combination medicine used to treat hypertension (high blood pressure).
Why is hydrochlorothiazide prescribed with lisinopril?
The combination of lisinopril and hydrochlorothiazide is used to treat high blood pressure. Lisinopril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly.
What is a good alternative to Flomax?
- alfuzosin (Uroxatral)
- doxazosin (Cardura)
- silodosin (Rapaflo)
- terazosin (Hytrin)
Is nitrofurantoin safe for sulfa allergy?
Other first line treatment options are available for patients with sulfonamide antimicrobial allergies diagnosed with uncomplicated cystitis, including nitrofurantoin and fosfomycin [9].
Can you take Flomax while nursing?
Can I take Tamsulosin (Flomax) if I’m pregnant or breastfeeding? Tamsulosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown.
Is amlodipine better than hydrochlorothiazide?
Conclusion: These results showed that for treatment of ISH in patients aged 60 years or more, amlodipine is significantly more effective than hydrochlorothiazide in reducing sitting SBP/DBP in monotherapy, and both drugs are well tolerated.
What's the difference between amlodipine besylate and amlodipine?
Amlodipine, marketed primarily as a besylate salt, is a calcium channel blocker used for treating essential hypertension. Amlodipine maleate is another salt that is considered, in terms of pharmacokinetics and pharmacodynamics, similar to amlodipine besylate.