Is Contrave a narcotic
Ava Robinson
Updated on April 15, 2026
Contrave (naltrexone HCl and bupropion HCl) Extended-release is a combination of an opioid antagonist and an antidepressant used as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index (BMI) of: 30 kg/m2 greater (obese) or 27 kg/m2 …
Is CONTRAVE a controlled substance?
Adding CONTRAVE to a diet and exercise plan has helped thousands of people lose weight and keep it off. And unlike other weight-loss medications, CONTRAVE is not a controlled substance, scheduled drug, or stimulant.
Is CONTRAVE a stimulant?
CONTRAVE, a combination of naltrexone HCl and bupropion HCl, targets the hypothalamus and mesolimbic reward system to give patients more control of their eating. Unlike other weight-loss medications, CONTRAVE is not a controlled substance, scheduled drug, or stimulant.
What class of drug is CONTRAVE?
Generic Name: naltrexone-bupropion Naltrexone belongs to a class of drugs known as opiate antagonists, and bupropion is an antidepressant that may help restore the balance of certain natural chemicals (neurotransmitters) in your brain.How does CONTRAVE make you feel?
Nearly 1 in 4 people in the clinical trials stopped taking the prescription weight loss pill because they couldn’t tolerate the common side effects, including nausea, headache, and vomiting. Contrave can also cause increased blood pressure, anxiety, and insomnia. Other side effects include constipation and dizziness.
Does contrave work immediately?
Contrave (naltrexone / bupropion) is used together with diet and exercise to help you lose weight. You can start to see weight loss as soon as 4 weeks after you start taking Contrave (naltrexone / bupropion).
What drugs are in contrave?
Contrave combines two drugs already on the market: bupropion (Wellbutrin), an antidepressant, and naltrexone, an anti-addiction drug. Because it contains bupropion, the new drug will have a boxed warning to alert doctors and patients to the increased risk of suicidal thoughts that are linked with antidepressants.
Is Contrave phentermine?
Contrave contains two ingredients: naltrexone and bupropion. Contrave does not contain phentermine.Can I stop contrave cold turkey?
If you are thinking about discontinuing your Wellbutrin treatment, talk to your doctor about gradually tapering off your dose over time. Bupropion should never be stopped cold-turkey unless you experience a seizure while taking Wellbutrin.
Has anyone died taking Contrave?In the off-treatment group, there were 12 cardiovascular deaths in the placebo group and 1 in the Contrave group. This isn’t surprising. When researchers want to take an early look at a clinical trial, the rules of statistical significance actually change.
Article first time published onIs phentermine a narcotic?
Phentermine is not a narcotic. Narcotics act on opioid receptors and are used to treat moderate to severe pain. Phentermine is a stimulant. It stimulates norepinephrine and epinephrine release and suppresses appetite.
Is Contrave like Wellbutrin?
CONTRAVE contains bupropion, the same active ingredient as some other antidepressant medications (including, but not limited to, WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, and APLENZIN). Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term trials.
What happens if you take Contrave with a high fat meal?
Do not take this medicine with a high-fat meal, or you may be more likely to have a seizure. If you need to use opioid medicine for any reason (such as pain, surgery, or treatment for drug addiction) you may need to stop taking bupropion and naltrexone for a short time.
Do you gain the weight back after Contrave?
If you stopped after a year of taking Contrave, you would very likely gain the weight right back. So if you wanted to keep that 10 pounds off for a long period of time, you have to take the medicine for presumably the rest of your life.
Does Contrave help with depression?
CONTRAVE is not approved to treat depression or other mental illnesses, or to help people quit smoking (smoking cessation). One of the ingredients in CONTRAVE, bupropion, is the same ingredient in some other medicines used to treat depression and to help people quit smoking.
Can I take Tylenol with Contrave?
acetaminophen naltrexone Naltrexone may cause liver problems, and using it with other medications that can also affect the liver such as acetaminophen may increase that risk.
What is the main ingredient in CONTRAVE?
The name of your medicine is CONTRAVE. It contains 2 active ingredients – bupropion hydrochloride and naltrexone hydrochloride. It is used in obese or overweight adults to manage weight together with a reduced calorie diet and physical exercise.
Can Contrave make you sleepy?
Common side effects of Contrave include nausea, constipation, headache, vomiting, insomnia, dry mouth, and diarrhea. Contrave can also cause changes in vision, drowsiness, and dizziness.
How much is Contrave a month?
The price of CONTRAVE is $99 per month (approximately $3 a day) through home delivery. For questions, call Ridgeway Mail Order Pharmacy at 1-800-630-3214. Have your prescription and insurance information ready. If your insurance covers CONTRAVE, then it may cost less than $99.
Does Contrave raise blood pressure?
CONTRAVE can cause an increase in systolic BP, diastolic BP, and/or resting HR. These events were observed in both patients with and without evidence of preexisting hypertension.
Does your brain go back to normal after antidepressants?
The process of healing the brain takes quite a bit longer than recovery from the acute symptoms. In fact, our best estimates are that it takes 6 to 9 months after you are no longer symptomatically depressed for your brain to entirely recover cognitive function and resilience.
Is Wellbutrin similar to Adderall?
Are Wellbutrin and Adderall the same? No. Wellbutrin is an antidepressant, and Adderall is a stimulant. They have differences in dosing, pricing, side effects, and drug interactions.
What happens if you drink on Wellbutrin?
Drinking alcohol with bupropion may increase your risk of seizures. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Bupropion can also cause seizures in a regular drinker who suddenly stops drinking at the start of treatment with bupropion.
How fast is weight loss on Wellbutrin?
A 2012 study found that obese adults who took bupropion SR (standard release) in 300mg or 400mg doses lost 7.2% and 10% of their body weight, respectively, over 24 weeks and maintained that weight loss at 48 weeks (Anderson, 2012).
Is there a generic form of Contrave?
Contrave is also a brand-only drug with no generic version on the market yet. Generic Contrave may not be available until 2030. Luckily, there are some ways for you to save.
Can I ask my doctor for weight loss pills?
Who is a candidate for weight-loss drugs? Your doctor may consider a weight-loss drug for you if you haven’t been able to lose weight through diet and exercise and you meet one of the following: Your body mass index (BMI) is greater than 30.
Does CONTRAVE make your heart race?
Contrave caused higher rates of elevated systolic blood pressure, rapid heart rate and palpitations in the Phase III trials. Similarly, prior to approval, Sibutramine had the same three increases in these cardiovascular risk factors.
Does CONTRAVE affect your heart?
Both of these medications have previously been found to have side effects that involve the heart and cardiovascular system. In particular, the effects of Contrave on heart rate and blood pressure appear to be unfavorable. In clinical trials, Contrave was found to increase both blood pressure and heart rate.
Can I stop CONTRAVE suddenly?
Do not change your CONTRAVE dose without talking with your healthcare provider. Your healthcare provider will change your dose if needed. Your healthcare provider should tell you to stop taking CONTRAVE if you have not lost a certain amount of weight after 16 weeks of treatment.
Can phentermine make you feel high?
Phentermine is absorbed through the gastrointestinal tract and reaches peak concentrations in the blood in three to 4.4 hours, by which time you should start feeling the effects, alerting you that the drug is working. The short-term effects of Adipex may include: Decreased appetite. Euphoria.
Is Saxenda a controlled substance?
Is Saxenda a Controlled Substance? No, Saxenda is not a controlled substance. Which Medications Should Not Be Used with Saxenda? Mediations used to treat type 2 diabetes called GLP1 receptor agonists or DPP4 inhibitors work similarly to Saxenda and should not be used together with Saxenda.